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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2064819Generated: November 2, 2026

2'-Fluorobiphenyl-2-carboxylic acid → benzofuran-4-carboxylic acid [(1S,3S,5S)-2-(2'-fluoro-biphenyl-2-carbonyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide

https://huagongshe.com/reaction/2064819

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2'-Fluorobiphenyl-2-carboxylic acidHCID 5109229—
Reactantbenzofuran-4-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amideHCID 67081492—
Productbenzofuran-4-carboxylic acid [(1S,3S,5S)-2-(2'-fluoro-biphenyl-2-carbonyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amideHCID 67081140—

Reaction Steps

prepared by reaction of benzofuran-4-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide with 2′-fluoro-biphenyl-2-carboxylic acid. LC-MS (basic): tR=1.43 min; [M+H]+=455.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288435B2
Source datasetuspto-grants-2012_10
ORD IDord-2add7a3af10e4c16ac5bfeab56ddc796
Source noteuspto-grants-2012_10