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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2064820Generated: November 2, 2026

2-(3-chlorophenyl)benzoic Acid → benzofuran-4-carboxylic acid [(1S,3S,5S)-2-(3'-chloro-biphenyl-2-carbonyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide

https://huagongshe.com/reaction/2064820

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-chlorophenyl)benzoic AcidHCID 2757415—
Reactantbenzofuran-4-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amideHCID 67081492—
Productbenzofuran-4-carboxylic acid [(1S,3S,5S)-2-(3'-chloro-biphenyl-2-carbonyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amideHCID 67081032—

Reaction Steps

prepared by reaction of benzofuran-4-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide with 3′-chloro-biphenyl-2-carboxylic acid. LC-MS (basic): tR=1.46 min; [M+H]+=471.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288435B2
Source datasetuspto-grants-2012_10
ORD IDord-e5a9b876be454362b7c18edfa6f527ec
Source noteuspto-grants-2012_10