HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-4-phenylpyrimidine-5-carboxylic acid → 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-(2-methyl-4-phenyl-pyrimidine-5-carbonyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-4-phenylpyrimidine-5-carboxylic acid | HCID 2776510 | — |
| Reactant | 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide | HCID 67080907 | — |
| Product | 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-(2-methyl-4-phenyl-pyrimidine-5-carbonyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide | HCID 67081352 | — |
Reaction Steps
prepared by reaction of 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide with 2-methyl-4-phenyl-pyrimidine-5-carboxylic acid. LC-MS (basic): tR=1.19 min; [M+H]+=473.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288435B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-ae4d8409107a42cc93b0d9b0414fc3a1 |
| Source note | uspto-grants-2012_10 |