HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Amino-thiazol-4-yl)-benzoic acid → 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid {(1S,3S,5S)-2-[2-(2-amino-thiazol-4-yl)-benzoyl]-2-aza-bicyclo[3.1.0]hex-3-ylmethyl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Amino-thiazol-4-yl)-benzoic acid | HCID 1409773 | — |
| Reactant | 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide | HCID 67080907 | — |
| Product | 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid {(1S,3S,5S)-2-[2-(2-amino-thiazol-4-yl)-benzoyl]-2-aza-bicyclo[3.1.0]hex-3-ylmethyl}-amide | HCID 86653651 | — |
Reaction Steps
prepared by reaction of 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide with 2-(2-amino-thiazol-4-yl)-benzoic acid. LC-MS (basic): tR=1.16 min; [M+H]+=479.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288435B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-d18eaf71eea8447da33123c46e2ee31f |
| Source note | uspto-grants-2012_10 |