2-Pyrazolylbenzoic acid → HCID 67081346, compound

HRID 2064832Notes

Reaction equation

HRID 2064832 reaction equation
[C@H:1]12[CH2:6][C@H:5]1[CH2:4][C@@H:3]([CH2:7][NH:8][C:9]([C:11]1[N:18]3[C:14]([S:15][CH:16]=[CH:17]3)=[N:13][C:12]=1[CH3:19])=[O:10])[NH:2]2.[N:20]1([C:25]2[CH:33]=[CH:32][CH:31]=[CH:30][C:26]=2[C:27](O)=[O:28])[CH:24]=[CH:23][CH:22]=[N:21]1>>[N:20]1([C:25]2[CH:33]=[CH:32][CH:31]=[CH:30][C:26]=2[C:27]([N:2]2[C@H:3]([CH2:7][NH:8][C:9]([C:11]3[N:18]4[C:14]([S:15][CH:16]=[CH:17]4)=[N:13][C:12]=3[CH3:19])=[O:10])[CH2:4][C@H:5]3[C@@H:1]2[CH2:6]3)=[O:28])[CH:24]=[CH:23][CH:22]=[N:21]1

Participants

3

Reactant 2

HCID 47383832-Pyrazolylbenzoic acidHCID 670809076-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide

Product 1

HCID 67081346HCID 67081346, compound

Procedure

prepared by reaction of 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide with 2-pyrazol-1-yl-benzoic acid. LC-MS (basic): tR=1.19 min; [M+H]+=447.1.

Sources & evidence

ORD record
ord-894bcb70ca1a494a914c75068e4c0299
Source dataset
uspto-grants-2012_10
Patent number
US08288435B2

Reaction notes

Loading…