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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2064863Generated: November 1, 2026

2,3-Dihydro-1-benzofuran-4-carboxylic acid → HCID 67081354, compound

https://huagongshe.com/reaction/2064863

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dihydro-1-benzofuran-4-carboxylic acidHCID 18787444—
Reactant[(1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl]-[5-(3-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanoneHCID 67081101—
ProductHCID 67081354HCID 67081354—

Reaction Steps

prepared by reaction of [(1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl]-[5-(3-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone with 2,3-dihydro-benzofuran-4-carboxylic acid (WO99/33460). LC-MS (basic): tR=0.88 min; [M+H]+=478.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288435B2
Source datasetuspto-grants-2012_10
ORD IDord-d0cef7bd98d04169a9dab118cde1babc
Source noteuspto-grants-2012_10