Benzoic acid, 2-amino-3-chloro-, methyl ester → Methyl 3-chloro-2-(8-(cyclopentyloxy)-7-methoxy-2-oxo-2H-chromen-4-ylamino)benzoate

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Reaction Steps

The title compound was prepared from methyl 2-amino-3-chlorobenzoate and 4-chloro-8-(cyclopentyloxy)-7-methoxy-2H-chromen-2-one following the procedure outlined in Example 16 (30 min r×n time). 1H NMR (400 MHz, DMSO-d6): δ 9.29 (s, 1H), 7.92 (m, 3H), 7.59 (t, 1H), 7.19 (d, 1H), 4.85 (m, 1H), 4.40 (s, 1H), 3.92 (s, 3H), 3.70 (s, 3H), 1.90-1.50 (m, 8H); MS (ESI): 443.9.

Provenance & Evidence