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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065177Generated: October 25, 2026

2-(Trifluoromethyl)cinnamic acid, (E)- → (E)-N-[1-(5-Oxo-hexyl)-1H-pyrazol-3-yl]-3-(2-trifluoromethyl-phenyl)-acrylamide

https://huagongshe.com/reaction/2065177

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)cinnamic acid, (E)-HCID 719625—
Reactant1-[4-(2-Methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-3-ylamineHCID 66928481—
Product(E)-N-[1-(5-Oxo-hexyl)-1H-pyrazol-3-yl]-3-(2-trifluoromethyl-phenyl)-acrylamideHCID 66928774—

Reaction Steps

Following general procedure B followed by either C or D, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-3-ylamine and (E)-3-(2-trifluoromethyl-phenyl)-acrylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-dc153d0ad6224de884969fa970165013
Source noteuspto-grants-2012_10