HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-fluorocinnamic acid → (E)-3-(2-Chloro-4-fluoro-phenyl)-N-[1-(5-oxo-hexyl)-1H-pyrazol-3-yl]-acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-fluorocinnamic acid | HCID 6257297 | — |
| Reactant | 1-[4-(2-Methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-3-ylamine | HCID 66928481 | — |
| Product | (E)-3-(2-Chloro-4-fluoro-phenyl)-N-[1-(5-oxo-hexyl)-1H-pyrazol-3-yl]-acrylamide | HCID 66928913 | — |
Reaction Steps
Following general procedure B followed by either C or D, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-3-ylamine and (E)-3-(2-chloro-4-fluoro-phenyl)-acrylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288419B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-22352037c05245cf8caa72677009590e |
| Source note | uspto-grants-2012_10 |