5-Phenyl-1,3-oxazole-4-carboxylic acid → HCID 66928155, compound
Reaction equation
[F:1][C:2]([F:14])([CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[CH:11]=[CH:10][C:9]([NH2:12])=[N:8]1.[C:15]1([C:21]2[O:25][CH:24]=[N:23][C:22]=2[C:26](O)=[O:27])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[F:14][C:2]([F:1])([CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[CH:11]=[CH:10][C:9]([NH:12][C:26]([C:22]2[N:23]=[CH:24][O:25][C:21]=2[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[O:27])=[N:8]1Participants
3
Procedure
Following general procedure B, starting from 1-(5,5-difluoro-hexyl)-1H-pyrazol-3-ylamine and 5-phenyl-oxazole-4-carboxylic acid.
Sources & evidence
- ORD record
- ord-e8affa18cd3e4b0a89afccdaa9b2e7b7
- Source dataset
- uspto-grants-2012_10
- Patent number
- US08288419B2
Reaction notes
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