2-Methyl-5-phenyl-1,3-oxazole-4-carboxylic acid → HCID 66928555, compound

HRID 2065199Notes

Reaction equation

HRID 2065199 reaction equation
[F:1][C:2]([F:14])([CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[CH:11]=[C:10]([NH2:12])[CH:9]=[N:8]1.[CH3:15][C:16]1[O:17][C:18]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[C:19]([C:21](O)=[O:22])[N:20]=1>>[F:14][C:2]([F:1])([CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[CH:11]=[C:10]([NH:12][C:21]([C:19]2[N:20]=[C:16]([CH3:15])[O:17][C:18]=2[C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)=[O:22])[CH:9]=[N:8]1

Participants

3

Reactant 2

HCID 156303442-Methyl-5-phenyl-1,3-oxazole-4-carboxylic acidHCID 669291721-(5,5-Difluoro-hexyl)-1H-pyrazol-4-ylamine

Product 1

HCID 66928555HCID 66928555, compound

Procedure

Following general procedure B, starting from 1-(5,5-difluoro-hexyl)-1H-pyrazol-4-ylamine and 2-methyl-5-phenyl-oxazole-4-carboxylic acid. LC-MS-conditions 05b: tR=1.14 min; [M+H]+=389.28.

Sources & evidence

ORD record
ord-df458dffd6a84016b0cbd27b57f6f366
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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