5-(3-Methoxyphenyl)oxazole-4-carboxylic acid → HCID 66929143, compound

HRID 2065202Notes

Reaction equation

HRID 2065202 reaction equation
[F:1][C:2]([F:14])([CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[CH:11]=[C:10]([NH2:12])[CH:9]=[N:8]1.[CH3:15][O:16][C:17]1[CH:18]=[C:19]([C:23]2[O:27][CH:26]=[N:25][C:24]=2[C:28](O)=[O:29])[CH:20]=[CH:21][CH:22]=1>>[F:14][C:2]([F:1])([CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[CH:11]=[C:10]([NH:12][C:28]([C:24]2[N:25]=[CH:26][O:27][C:23]=2[C:19]2[CH:20]=[CH:21][CH:22]=[C:17]([O:16][CH3:15])[CH:18]=2)=[O:29])[CH:9]=[N:8]1

Participants

3

Reactant 2

HCID 616373645-(3-Methoxyphenyl)oxazole-4-carboxylic acidHCID 669291721-(5,5-Difluoro-hexyl)-1H-pyrazol-4-ylamine

Product 1

HCID 66929143HCID 66929143, compound

Procedure

Following general procedure B, starting from 1-(5,5-difluoro-hexyl)-1H-pyrazol-4-ylamine and 5-(3-methoxy-phenyl)-oxazole-4-carboxylic acid. LC-MS-conditions 05b: tR=1.12 min; [M+H]+=405.24.

Sources & evidence

ORD record
ord-8d6e7490b1054e3bbfb8ee8fc5eaa28c
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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