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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065216Generated: October 25, 2026

m-(Trifluoromethyl)cinnamic acid → (E)-N-[1-(5,5-Difluoro-hexyl)-1H-pyrazol-3-yl]-3-(3-trifluoromethyl-phenyl)-acrylamide

https://huagongshe.com/reaction/2065216

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-(Trifluoromethyl)cinnamic acidHCID 719451—
Reactant1-(5,5-Difluoro-hexyl)-1H-pyrazol-3-ylamineHCID 66928304—
Product(E)-N-[1-(5,5-Difluoro-hexyl)-1H-pyrazol-3-yl]-3-(3-trifluoromethyl-phenyl)-acrylamideHCID 66929080—

Reaction Steps

Following general procedure B, starting from 1-(5,5-difluoro-hexyl)-1H-pyrazol-3-ylamine and (E)-3-(3-trifluoromethyl-phenyl)-acrylic acid. LC-MS-conditions 05b: tR=1.15 min; [M+H]+=402.06.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-f5264fd17d3246c3949c6c7070b5d997
Source noteuspto-grants-2012_10