1-[4-(2-Methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-4-ylamine → HCID 66929082, compound

HRID 2065220Notes

Reaction equation

HRID 2065220 reaction equation
[CH3:1][C:2]1([CH2:7][CH2:8][CH2:9][CH2:10][N:11]2[CH:15]=[C:14]([NH2:16])[CH:13]=[N:12]2)[O:6]CCO1.[Cl:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[O:28][C:27]([CH3:29])=[N:26][C:25]=2[C:30](O)=[O:31])=[CH:20][CH:19]=1>>[O:6]=[C:2]([CH3:1])[CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[CH:15]=[C:14]([NH:16][C:30]([C:25]2[N:26]=[C:27]([CH3:29])[O:28][C:24]=2[C:21]2[CH:22]=[CH:23][C:18]([Cl:17])=[CH:19][CH:20]=2)=[O:31])[CH:13]=[N:12]1

Participants

3

Reactant 2

HCID 669287261-[4-(2-Methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-4-ylamineHCID 66929039HCID 66929039, compound

Product 1

HCID 66929082HCID 66929082, compound

Procedure

Following general procedure B followed by either C or D, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-4-ylamine and 5-(4-chloro-phenyl)-2-methyl-oxazole-4-carboxylic acid. LC-MS-conditions 01: tR=0.99 min; [M+H]+=401.13.

Sources & evidence

ORD record
ord-dff008e754e34c4f9b42462173a3cd95
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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