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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065231Generated: October 26, 2026

5-(4-Methoxyphenyl)-1,3-oxazole-4-carboxylic acid → 5-(4-Methoxy-phenyl)-oxazole-4-carboxylic acid {1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-yl}-amide

https://huagongshe.com/reaction/2065231

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Methoxyphenyl)-1,3-oxazole-4-carboxylic acidHCID 2779782—
Reactant1-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamineHCID 66928549—
Product5-(4-Methoxy-phenyl)-oxazole-4-carboxylic acid {1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-yl}-amideHCID 66928576—

Reaction Steps

Following general procedure B, starting from 1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine and 5-(4-methoxy-phenyl)-oxazole-4-carboxylic acid. LC-MS-conditions 05b: tR=1.11 min; [M+H]+=429.03.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-5f0869b613d044a28f364ce67895d3f4
Source noteuspto-grants-2012_10