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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065236Generated: October 27, 2026

1-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine → 5-(3-Methoxy-phenyl)-2-methyl-oxazole-4-carboxylic acid {1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-yl}-amide

https://huagongshe.com/reaction/2065236

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamineHCID 66928549—
Reactant5-(3-Methoxy-phenyl)-2-methyl-oxazole-4-carboxylic acidHCID 66929224—
Product5-(3-Methoxy-phenyl)-2-methyl-oxazole-4-carboxylic acid {1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-yl}-amideHCID 66928522—

Reaction Steps

Following general procedure B, starting from 1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine and 5-(3-methoxy-phenyl)-2-methyl-oxazole-4-carboxylic acid. LC-MS-conditions 05b: tR=1.15 min; [M+H]+=443.03.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-c49b0203a04349a4a6301aeef8940043
Source noteuspto-grants-2012_10