4-Methoxycinnamic Acid → HCID 66929042, compound

HRID 2065252Notes

Reaction equation

HRID 2065252 reaction equation
[F:1][C:2]([C:5]1[O:9][C:8]([CH2:10][N:11]2[CH:15]=[CH:14][C:13]([NH2:16])=[N:12]2)=[CH:7][CH:6]=1)([F:4])[CH3:3].[CH3:17][O:18][C:19]1[CH:24]=[CH:23][C:22](/[CH:25]=[CH:26]/[C:27](O)=[O:28])=[CH:21][CH:20]=1>>[F:4][C:2]([C:5]1[O:9][C:8]([CH2:10][N:11]2[CH:15]=[CH:14][C:13]([NH:16][C:27](=[O:28])/[CH:26]=[CH:25]/[C:22]3[CH:23]=[CH:24][C:19]([O:18][CH3:17])=[CH:20][CH:21]=3)=[N:12]2)=[CH:7][CH:6]=1)([F:1])[CH3:3]

Participants

3

Reactant 2

HCID 6994144-Methoxycinnamic AcidHCID 669293691-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine

Product 1

HCID 66929042HCID 66929042, compound

Procedure

Following general procedure B, starting from 1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine and (E)-3-(4-methoxy-phenyl)-acrylic acid. LC-MS-conditions 05b: tR=1.08 min; [M+H]+=388.12.

Sources & evidence

ORD record
ord-125b1912fad64bbb824ef165e60408b8
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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