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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065257Generated: November 1, 2026

5-(3-Methoxyphenyl)oxazole-4-carboxylic acid → 5-(3-Methoxy-phenyl)-oxazole-4-carboxylic acid {1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-yl}-amide

https://huagongshe.com/reaction/2065257

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(3-Methoxyphenyl)oxazole-4-carboxylic acidHCID 61637364—
Reactant1-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamineHCID 66928549—
Product5-(3-Methoxy-phenyl)-oxazole-4-carboxylic acid {1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-yl}-amideHCID 66929054—

Reaction Steps

Following general procedure B, starting from 1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine and 5-(3-methoxy-phenyl)-oxazole-4-carboxylic acid. LC-MS-conditions 05b: tR=1.12 min; [M+H]+=429.04.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-376eb60fb5e04dbfbd182244f105bc70
Source noteuspto-grants-2012_10