5-[4-(Trifluoromethoxy)phenyl]-1,3-oxazole-4-carboxylic acid → HCID 66928780, compound

HRID 2065285Notes

Reaction equation

HRID 2065285 reaction equation
[CH3:1][C:2]1([C:7]2[O:11][C:10]([CH2:12][N:13]3[CH:17]=[C:16]([NH2:18])[CH:15]=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[F:19][C:20]([F:37])([F:36])[O:21][C:22]1[CH:27]=[CH:26][C:25]([C:28]2[O:32][CH:31]=[N:30][C:29]=2[C:33](O)=[O:34])=[CH:24][CH:23]=1>>[C:2]([C:7]1[O:11][C:10]([CH2:12][N:13]2[CH:17]=[C:16]([NH:18][C:33]([C:29]3[N:30]=[CH:31][O:32][C:28]=3[C:25]3[CH:24]=[CH:23][C:22]([O:21][C:20]([F:36])([F:19])[F:37])=[CH:27][CH:26]=3)=[O:34])[CH:15]=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 269851625-[4-(Trifluoromethoxy)phenyl]-1,3-oxazole-4-carboxylic acidHCID 669286111-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine

Product 1

HCID 66928780HCID 66928780, compound

Procedure

Following general procedure B followed by T, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine and 5-(4-trifluoromethoxy-phenyl)-oxazole-4-carboxylic acid. LC-MS-conditions 01b: tR=1.01 min; [M+H]+=461.11.

Sources & evidence

ORD record
ord-145432bf53d04cbbbb8b807d897f1ba3
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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