5-(3-Chloro-phenyl)-2-methyl-oxazole-4-carboxylic acid → HCID 66928807, compound

HRID 2065294Notes

Reaction equation

HRID 2065294 reaction equation
[CH3:1][C:2]1([C:7]2[O:11][C:10]([CH2:12][N:13]3[CH:17]=[CH:16][C:15]([NH2:18])=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[CH3:19][C:20]1[O:21][C:22]([C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([Cl:34])[CH:29]=2)=[C:23]([C:25](O)=[O:26])[N:24]=1>>[C:2]([C:7]1[O:11][C:10]([CH2:12][N:13]2[CH:17]=[CH:16][C:15]([NH:18][C:25]([C:23]3[N:24]=[C:20]([CH3:19])[O:21][C:22]=3[C:28]3[CH:33]=[CH:32][CH:31]=[C:30]([Cl:34])[CH:29]=3)=[O:26])=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 534307265-(3-Chloro-phenyl)-2-methyl-oxazole-4-carboxylic acidHCID 669287811-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine

Product 1

HCID 66928807HCID 66928807, compound

Procedure

Following general procedure B followed by T, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine and 2-methyl-5-(3-chloro-phenyl)-oxazole-4-carboxylic acid. LC-MS-conditions 05b (with gradient: 5% B→95% B over 1 min): tR=0.79 min; [M+H]+=425.14.

Sources & evidence

ORD record
ord-b1556c6747f844feacbe0b0010ba8ffd
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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