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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065323Generated: November 1, 2026

5-(m-Tolyl)oxazole-4-carboxylic acid → 5-m-Tolyl-oxazole-4-carboxylic acid [1-(5-acetyl-thiophen-2-ylmethyl)-1H-pyrazol-4-yl]-amide

https://huagongshe.com/reaction/2065323

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(m-Tolyl)oxazole-4-carboxylic acidHCID 29923092—
ReactantHCID 66928512HCID 66928512—
Product5-m-Tolyl-oxazole-4-carboxylic acid [1-(5-acetyl-thiophen-2-ylmethyl)-1H-pyrazol-4-yl]-amideHCID 66928374—

Reaction Steps

Following general procedure X followed by C, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-1H-pyrazol-4-ylamine and 5-m-tolyl-oxazole-4-carboxylic acid. LC-MS-conditions 05c: tR=0.72 min; [M+H]+=407.20.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-999531cac9ea4dd9bccde8480de62fa9
Source noteuspto-grants-2012_10