5-(m-Tolyl)oxazole-4-carboxylic acid → HCID 66929139, compound

HRID 2065324Notes

Reaction equation

HRID 2065324 reaction equation
[CH3:1][C:2]1([C:7]2[S:11][C:10]([CH2:12][N:13]3[CH:17]=[CH:16][C:15]([NH2:18])=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[C:19]1([CH3:33])[CH:24]=[CH:23][CH:22]=[C:21]([C:25]2[O:29][CH:28]=[N:27][C:26]=2[C:30](O)=[O:31])[CH:20]=1>>[C:2]([C:7]1[S:11][C:10]([CH2:12][N:13]2[CH:17]=[CH:16][C:15]([NH:18][C:30]([C:26]3[N:27]=[CH:28][O:29][C:25]=3[C:21]3[CH:20]=[C:19]([CH3:33])[CH:24]=[CH:23][CH:22]=3)=[O:31])=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 299230925-(m-Tolyl)oxazole-4-carboxylic acidHCID 66929157HCID 66929157, compound

Product 1

HCID 66929139HCID 66929139, compound

Procedure

Following general procedure X followed by C, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-1H-pyrazol-3-ylamine and 5-m-tolyl-oxazole-4-carboxylic acid. LC-MS-conditions 05c: tR=0.75 min; [M+H]+=407.22.

Sources & evidence

ORD record
ord-6de1575261d145c78ef0a10ee012f6b5
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

Loading…