HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid → 2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid [1-(5-acetyl-thiophen-2-ylmethyl)-1H-pyrazol-4-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid | HCID 53271816 | — |
| Reactant | HCID 66928512 | HCID 66928512 | — |
| Product | 2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid [1-(5-acetyl-thiophen-2-ylmethyl)-1H-pyrazol-4-yl]-amide | HCID 66928800 | — |
Reaction Steps
Following general procedure X followed by C, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-1H-pyrazol-4-ylamine and 2-methyl-5-m-tolyl-thiazole-4-carboxylic acid. LC-MS-conditions 05c: tR=0.75 min; [M+H]+=437.22.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288419B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-b5b187af0c9442df865c4f4ac08a6ff5 |
| Source note | uspto-grants-2012_10 |