HCID 22282498, compound → HCID 66928247, compound

HRID 2065328Notes

Reaction equation

HRID 2065328 reaction equation
[CH3:1][C:2]1([C:7]2[S:11][C:10]([CH2:12][N:13]3[CH:17]=[CH:16][C:15]([NH2:18])=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[C:19]([C:21]1[CH:22]=[C:23]([C:27]2[O:31][CH:30]=[N:29][C:28]=2[C:32](O)=[O:33])[CH:24]=[CH:25][CH:26]=1)#[N:20]>>[C:2]([C:7]1[S:11][C:10]([CH2:12][N:13]2[CH:17]=[CH:16][C:15]([NH:18][C:32]([C:28]3[N:29]=[CH:30][O:31][C:27]=3[C:23]3[CH:24]=[CH:25][CH:26]=[C:21]([C:19]#[N:20])[CH:22]=3)=[O:33])=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 22282498HCID 22282498, compoundHCID 66929157HCID 66929157, compound

Product 1

HCID 66928247HCID 66928247, compound

Procedure

Following general procedure X followed by C, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-1H-pyrazol-3-ylamine and 5-(3-cyano-phenyl)-oxazole-4-carboxylic acid. LC-MS-conditions 05c: tR=0.70 min; [M+H]+=417.70.

Sources & evidence

ORD record
ord-04d06aa5fc5e40f79b035f3c36b60ddd
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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