1-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine → HCID 66929181, compound

HRID 2065334Notes

Reaction equation

HRID 2065334 reaction equation
[CH3:1][C:2]1([C:7]2[O:11][C:10]([CH2:12][N:13]3[CH:17]=[CH:16][C:15]([NH2:18])=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.C([SiH2][O:24][C:25](C)(C)[C:26]1[CH:27]=[C:28]([C:32]2[O:36][CH:35]=[N:34][C:33]=2[C:37](O)=[O:38])[CH:29]=[CH:30][CH:31]=1)(C)(C)C>>[C:2]([C:7]1[O:11][C:10]([CH2:12][N:13]2[CH:17]=[CH:16][C:15]([NH:18][C:37]([C:33]3[N:34]=[CH:35][O:36][C:32]=3[C:28]3[CH:29]=[CH:30][CH:31]=[C:26]([CH2:25][OH:24])[CH:27]=3)=[O:38])=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 669287811-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamineHCID 178455423HCID 178455423, compound

Product 1

HCID 66929181HCID 66929181, compound

Procedure

Following general procedure B followed by C, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine and 5-[3-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-oxazole-4-carboxylic acid. LC-MS-conditions 02: tR=0.86 min; [M+H]+=407.37.

Sources & evidence

ORD record
ord-470a4b314b424b1590946c931090949f
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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