1-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine → HCID 66929278, compound

HRID 2065340Notes

Reaction equation

HRID 2065340 reaction equation
[CH3:1][C:2]1([C:7]2[O:11][C:10]([CH2:12][N:13]3[CH:17]=[C:16]([NH2:18])[CH:15]=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[F:19][C:20]1[CH:25]=[C:24]([C:26]2[O:30][CH:29]=[N:28][C:27]=2[C:31](O)=[O:32])[CH:23]=[CH:22][N:21]=1>>[C:2]([C:7]1[O:11][C:10]([CH2:12][N:13]2[CH:17]=[C:16]([NH:18][C:31]([C:27]3[N:28]=[CH:29][O:30][C:26]=3[C:24]3[CH:23]=[CH:22][N:21]=[C:20]([F:19])[CH:25]=3)=[O:32])[CH:15]=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 669286111-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamineHCID 66929177HCID 66929177, compound

Product 1

HCID 66929278HCID 66929278, compound

Procedure

Following general procedure B followed by C, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine and 5-(2-fluoro-pyridin-4-yl)-oxazole-4-carboxylic acid. LC-MS-conditions 02: tR=0.90 min; [M+H]+=395.98.

Sources & evidence

ORD record
ord-d2520d6c0394451e8919d7ee6b4b4c46
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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