1-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine → HCID 66928966, compound

HRID 2065343Notes

Reaction equation

HRID 2065343 reaction equation
[CH3:1][C:2]1([C:7]2[O:11][C:10]([CH2:12][N:13]3[CH:17]=[C:16]([NH2:18])[CH:15]=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[Li+].[CH3:20][C:21]1[N:26]=[C:25]([C:27]2[O:31][CH:30]=[N:29][C:28]=2[C:32]([O-])=[O:33])[CH:24]=[CH:23][CH:22]=1>>[C:2]([C:7]1[O:11][C:10]([CH2:12][N:13]2[CH:17]=[C:16]([NH:18][C:32]([C:28]3[N:29]=[CH:30][O:31][C:27]=3[C:25]3[CH:24]=[CH:23][CH:22]=[C:21]([CH3:20])[N:26]=3)=[O:33])[CH:15]=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 669286111-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamineHCID 66929368HCID 66929368, compound

Product 1

HCID 66928966HCID 66928966, compound

Procedure

Following general procedure Z3 followed by C, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine and 5-(6-methyl-pyridin-2-yl)-oxazole-4-carboxylic acid lithium salt. LC-MS-conditions 02: tR=0.75 min; [M+H]+=392.31.

Sources & evidence

ORD record
ord-dbc09fbf6ffa4be592bdc8f9deff246b
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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