1-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine → HCID 66928727, compound

HRID 2065348Notes

Reaction equation

HRID 2065348 reaction equation
[CH3:1][C:2]1([C:7]2[O:11][C:10]([CH2:12][N:13]3[CH:17]=[C:16]([NH2:18])[CH:15]=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[Li+].[O:20]1[C:24]([C:25]2[O:29][CH:28]=[N:27][C:26]=2[C:30]([O-])=[O:31])=[CH:23][CH:22]=[N:21]1>>[C:2]([C:7]1[O:11][C:10]([CH2:12][N:13]2[CH:17]=[C:16]([NH:18][C:30]([C:26]3[N:27]=[CH:28][O:29][C:25]=3[C:24]3[O:20][N:21]=[CH:22][CH:23]=3)=[O:31])[CH:15]=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 669286111-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamineHCID 66929311HCID 66929311, compound

Product 1

HCID 66928727HCID 66928727, compound

Procedure

Following general procedure Z3 followed by C, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine and 5-isoxazol-5-yl-oxazole-4-carboxylic acid lithium salt. LC-MS-conditions 01: tR=0.81 min; [M+H]+=367.95.

Sources & evidence

ORD record
ord-65f377486be146e587c27d898d1e13e3
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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