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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065349Generated: November 1, 2026

5-Phenyl-1,3-oxazole-4-carboxylic acid → 5-Phenyl-oxazole-4-carboxylic acid [1-(2-acetyl-thiazol-4-ylmethyl)-1H-pyrazol-3-yl]-amide

https://huagongshe.com/reaction/2065349

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Phenyl-1,3-oxazole-4-carboxylic acidHCID 2776299—
Reactant1-[2-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-4-ylmethyl]-1H-pyrazol-3-ylamineHCID 66928650—
Product5-Phenyl-oxazole-4-carboxylic acid [1-(2-acetyl-thiazol-4-ylmethyl)-1H-pyrazol-3-yl]-amideHCID 66928674—

Reaction Steps

Following general procedure B followed by C, starting from 1-[2-(2-methyl-[1,3]dioxolan-2-yl)-thiazol-4-ylmethyl]-1H-pyrazol-3-ylamine and 5-phenyl-oxazole-4-carboxylic acid. LC-MS-conditions 02: tR=1.0 min; [M+H]+=394.25.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-9737283a00ec4d368dba8b5496befbfe
Source noteuspto-grants-2012_10