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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065358Generated: October 25, 2026

5-Phenyl-1,3-oxazole-4-carboxylic acid → 5-Phenyl-oxazole-4-carboxylic acid [1-(4-acetyl-thiazol-2-ylmethyl)-1H-pyrazol-3-yl]-amide

https://huagongshe.com/reaction/2065358

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Phenyl-1,3-oxazole-4-carboxylic acidHCID 2776299—
Reactant1-[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamineHCID 66928995—
Product5-Phenyl-oxazole-4-carboxylic acid [1-(4-acetyl-thiazol-2-ylmethyl)-1H-pyrazol-3-yl]-amideHCID 66928273—

Reaction Steps

Following general procedure B followed by C, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine and 5-phenyl-oxazole-4-carboxylic acid. LC-MS-conditions 01: tR=0.92 min; [M+H]+=393.99.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-647c31b25f70424aae37c3ccec9de11b
Source noteuspto-grants-2012_10