HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Phenyl-1,3-oxazole-4-carboxylic acid → 5-Phenyl-oxazole-4-carboxylic acid [1-(2-acetyl-thiazol-5-ylmethyl)-1H-pyrazol-4-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Phenyl-1,3-oxazole-4-carboxylic acid | HCID 2776299 | — |
| Reactant | 1-[2-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-5-ylmethyl]-1H-pyrazol-4-ylamine | HCID 66929332 | — |
| Product | 5-Phenyl-oxazole-4-carboxylic acid [1-(2-acetyl-thiazol-5-ylmethyl)-1H-pyrazol-4-yl]-amide | HCID 66928146 | — |
Reaction Steps
Following general procedure B followed by C, starting from 1-[2-(2-methyl-[1,3]dioxolan-2-yl)-thiazol-5-ylmethyl]-1H-pyrazol-4-ylamine and 5-phenyl-oxazole-4-carboxylic acid. LC-MS-conditions 02: tR=0.98 min; [M+H]+=393.91.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288419B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-ed919a9ec9064fee8bbbf9a97d169c53 |
| Source note | uspto-grants-2012_10 |