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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065367Generated: October 25, 2026

1-[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine → 2-Methyl-5-m-tolyl-oxazole-4-carboxylic acid [1-(4-acetyl-thiazol-2-ylmethyl)-1H-pyrazol-3-yl]-amide

https://huagongshe.com/reaction/2065367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamineHCID 66928995—
Reactant2-Methyl-5-(m-tolyl)oxazole-4-carboxylic acidHCID 66929205—
Product2-Methyl-5-m-tolyl-oxazole-4-carboxylic acid [1-(4-acetyl-thiazol-2-ylmethyl)-1H-pyrazol-3-yl]-amideHCID 66929077—

Reaction Steps

Following general procedure B followed by C, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine and 2-methyl-5-m-tolyl-oxazole-4-carboxylic acid. LC-MS-conditions 05: tR=0.92 min; [M+H]+=422.07.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-c21becb820a945279e603c7ab4514839
Source noteuspto-grants-2012_10