HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-5-phenyl-1,3-oxazole-4-carboxylic acid → 2-Methyl-5-phenyl-oxazole-4-carboxylic acid [1-(4-acetyl-thiazol-2-ylmethyl)-1H-pyrazol-3-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-5-phenyl-1,3-oxazole-4-carboxylic acid | HCID 15630344 | — |
| Reactant | 1-[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine | HCID 66928995 | — |
| Product | 2-Methyl-5-phenyl-oxazole-4-carboxylic acid [1-(4-acetyl-thiazol-2-ylmethyl)-1H-pyrazol-3-yl]-amide | HCID 66928309 | — |
Reaction Steps
Following general procedure B followed by C, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine and 2-methyl-5-phenyl-oxazole-4-carboxylic acid. LC-MS-conditions 05: tR=0.87 min; [M+H]+=408.12.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288419B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-596b81aa007749538733938d8d0b8622 |
| Source note | uspto-grants-2012_10 |