5-(3-Dimethylamino-phenyl)-oxazole-4-carboxylic acid → HCID 66928823, compound

HRID 2065373Notes

Reaction equation

HRID 2065373 reaction equation
[CH3:1][C:2]1([C:7]2[N:8]=[C:9]([CH2:12][N:13]3[CH:17]=[CH:16][C:15]([NH2:18])=[N:14]3)[S:10][CH:11]=2)[O:6]CCO1.[CH3:19][N:20]([CH3:35])[C:21]1[CH:22]=[C:23]([C:27]2[O:31][CH:30]=[N:29][C:28]=2[C:32](O)=[O:33])[CH:24]=[CH:25][CH:26]=1>>[C:2]([C:7]1[N:8]=[C:9]([CH2:12][N:13]2[CH:17]=[CH:16][C:15]([NH:18][C:32]([C:28]3[N:29]=[CH:30][O:31][C:27]=3[C:23]3[CH:24]=[CH:25][CH:26]=[C:21]([N:20]([CH3:35])[CH3:19])[CH:22]=3)=[O:33])=[N:14]2)[S:10][CH:11]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 532113435-(3-Dimethylamino-phenyl)-oxazole-4-carboxylic acidHCID 669289951-[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine

Product 1

HCID 66928823HCID 66928823, compound

Procedure

Following general procedure B followed by C, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine and 5-(3-dimethylamino-phenyl)-oxazole-4-carboxylic acid. LC-MS-conditions 05: tR=0.68 min; [M+H]+=437.04.

Sources & evidence

ORD record
ord-6fcaefb841394add86b306641dfe3f10
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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