1-[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine → HCID 66928872, compound

HRID 2065382Notes

Reaction equation

HRID 2065382 reaction equation
[CH3:1][C:2]1([C:7]2[N:8]=[C:9]([CH2:12][N:13]3[CH:17]=[CH:16][C:15]([NH2:18])=[N:14]3)[S:10][CH:11]=2)[O:6]CCO1.[CH3:19][O:20][C:21]1[CH:22]=[C:23]([C:27]2[O:31][C:30]([CH3:32])=[N:29][C:28]=2[C:33](O)=[O:34])[CH:24]=[CH:25][CH:26]=1>>[C:2]([C:7]1[N:8]=[C:9]([CH2:12][N:13]2[CH:17]=[CH:16][C:15]([NH:18][C:33]([C:28]3[N:29]=[C:30]([CH3:32])[O:31][C:27]=3[C:23]3[CH:24]=[CH:25][CH:26]=[C:21]([O:20][CH3:19])[CH:22]=3)=[O:34])=[N:14]2)[S:10][CH:11]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 669289951-[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamineHCID 669292245-(3-Methoxy-phenyl)-2-methyl-oxazole-4-carboxylic acid

Product 1

HCID 66928872HCID 66928872, compound

Procedure

Following general procedure B followed by C, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine and 5-(3-methoxy-phenyl)-2-methyl-oxazole-4-carboxylic acid. LC-MS-conditions 05: tR=0.87 min; [M+H]+=438.02.

Sources & evidence

ORD record
ord-64ca0104ef5c4632b93badd4ff4b0ce4
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Reaction notes

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