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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065454Generated: November 2, 2026

HCID 86086990, compound → HCID 66743353, compound

https://huagongshe.com/reaction/2065454

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86086990HCID 86086990—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 66743353HCID 66743353112.5%

Reaction Steps

A mixture of 4′-azido-3H-spiro[2-benzofuran-1,1′-cyclohexan]-3-one (90 mg, 0.36 mmol) in methanol (5 mL) with 10% palladium on charcoal (30 mg) was stirred under hydrogen atmosphere (balloon) for 1 hour. After filtration, the solution was concentrated to yield 88 mg of 4′-amino-3H-spiro[2-benzofuran-1,1′-cyclohexan]-3-one (yield: 90%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288417B2
Source datasetuspto-grants-2012_10
ORD IDord-2c1dfaae1f514d64b11e17f7395e480c
Source noteuspto-grants-2012_10