HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenylglycine → 2-[(Carboxy-phenyl-methyl)-amino]-6-chloro-quinoline-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenylglycine | HCID 3866 | — |
| Reactant | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Product | 2-[(Carboxy-phenyl-methyl)-amino]-6-chloro-quinoline-3-carboxylic acid | HCID 45256875 | 33% |
Reaction Steps
In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with DL-phenylglycine to provide the title compound in 33% yield as yellow needles (recrystallization from DMF/water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-4c4ba31ec50b4fb9a7bc0ee05d0fc958 |
| Source note | uspto-grants-2012_10 |