HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroform → HCID 45256877, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | (R)-beta-aminophenethyl alcohol | HCID 2724025 | — |
| Reactant | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 45256877 | HCID 45256877 | 23% |
Reaction Steps
In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with D-phenylglycinol to provide the title compound in 23% yield as yellow needles (flash chromatography on SiO2, eluent CHCl3, MeOH, AcOH—15, 1, 0.2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-7e77e9e98623405b882fc394514b756d |
| Source note | uspto-grants-2012_10 |