HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → HCID 45257057, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | D-Tryptophan | HCID 9060 | — |
| Reactant | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 45257057 | HCID 45257057 | 17% |
Reaction Steps
In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with D-tryptophan to provide the title compound in 17% yield as yellow needles (flash chromatography on SiO2, eluent MeCN, H2O, AcOH—20, 1, 0.3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-c46bc26e937e4c988873f4ebfe00c803 |
| Source note | uspto-grants-2012_10 |