HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Benzyl-D-serine → 2-((R)-2-Benzyloxy-1-carboxy-ethylamino)-6-chloro-quinoline-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Benzyl-D-serine | HCID 112114 | — |
| Reactant | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Product | 2-((R)-2-Benzyloxy-1-carboxy-ethylamino)-6-chloro-quinoline-3-carboxylic acid | HCID 45254181 | 34% |
Reaction Steps
In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with O-benzyl-D-serine to provide the title compound in 34% yield as yellow needles (recrystallization from DMF/water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-85312199da0c47b5a07bbe78d0550ea6 |
| Source note | uspto-grants-2012_10 |