HuagongsheHuagongshe Chemistry Print Report · For research reference only
DL-alanine → HCID 45254377, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | DL-alanine | HCID 602 | — |
| Reactant | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Product | HCID 45254377 | HCID 45254377 | 14% |
Reaction Steps
In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with DL-2-aminopropionic acid to provide the title compound in 14% yield as yellow needles (flash chromatography on SiO2, eluent CHCl3, MeOH, AcOH—10, 1, 0.2 and recrystallization from DMF/water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-96ba688f52684e0aa09f6273fbff00f6 |
| Source note | uspto-grants-2012_10 |