HuagongsheHuagongshe Chemistry Print Report · For research reference only
Homophenylalanine, DL- → 2-(1-Carboxy-3-phenyl-propylamino)-6-chloro-quinoline-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Homophenylalanine, DL- | HCID 102530 | — |
| Reactant | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Product | 2-(1-Carboxy-3-phenyl-propylamino)-6-chloro-quinoline-3-carboxylic acid | HCID 45254379 | 77% |
Reaction Steps
In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with DL-homophenylalanine to provide the title compound in 77% yield as yellow needles (recrystallization from EtOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-75041df39ec84b729677ee3f518288c4 |
| Source note | uspto-grants-2012_10 |