2,3-Diaminopropionic acid → HCID 131730019, compound

HRID 2065622Notes

Reaction equation

HRID 2065622 reaction equation
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[CH2:16]([NH2:22])[CH:17]([NH2:21])[C:18]([OH:20])=[O:19]>>[NH4+:3].[C:18]([CH:17]([NH:21][C:2]1[C:11]([C:12]([O-:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)[CH2:16][NH:22][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)([OH:20])=[O:19]

Participants

3

Reactant 2

HCID 3642,3-Diaminopropionic acidHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

Product 1

HCID 131730019HCID 131730019, compoundYield 23%

Procedure

In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with DL-2,3-diaminopropionic acid to provide the title compound in 23% yield as yellow needles (recrystallization from MeOH/water/NH4OH).

Sources & evidence

ORD record
ord-21cd6ec9a54940f1b8cf4e07082c4160
Source dataset
uspto-grants-2012_10
Patent number
US08288549B2

Reaction notes

Loading…