3-Nitro-L-tyrosine → HCID 45254750, compound

HRID 2065625Notes

Reaction equation

HRID 2065625 reaction equation
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[N+:16]([C:19]1[CH:20]=[C:21]([CH:28]=[CH:29][C:30]=1[OH:31])[CH2:22][C@@H:23]([C:25]([OH:27])=[O:26])[NH2:24])([O-:18])=[O:17]>>[C:25]([C@@H:23]([NH:24][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)[CH2:22][C:21]1[CH:28]=[CH:29][C:30]([OH:31])=[C:19]([N+:16]([O-:18])=[O:17])[CH:20]=1)([OH:27])=[O:26]

Participants

3

Reactant 2

HCID 651243-Nitro-L-tyrosineHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

Product 1

HCID 45254750HCID 45254750, compoundYield 10%

Procedure

In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 3-nitro-L-tyrosine to provide the title compound in 10% yield as yellow needles.

Sources & evidence

ORD record
ord-ceabb24cea8843748fa651483a9f1403
Source dataset
uspto-grants-2012_10
Patent number
US08288549B2

Reaction notes

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