HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Phenylalanine → 2-((S)-1-Carboxy-2-phenyl-ethylamino)-6,8-dichloro-quinoline-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Phenylalanine | HCID 6140 | — |
| Reactant | 2,6,8-Trichloroquinoline-3-carboxylic acid | HCID 86656379 | — |
| Product | 2-((S)-1-Carboxy-2-phenyl-ethylamino)-6,8-dichloro-quinoline-3-carboxylic acid | HCID 45254751 | 39% |
Reaction Steps
In close analogy to the procedure described in Example 1, 2,6,8-trichloroquinoline-3-carboxylic acid is reacted with L-phenylalanine to provide the title compound in 39% yield as yellow needles (recrystallization from EtOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-20ea73f8ae5c4a1dbcd3994d5ce31b27 |
| Source note | uspto-grants-2012_10 |