3-(3-Carboxyphenyl)alanine → HCID 45255381, compound

HRID 2065640Notes

Reaction equation

HRID 2065640 reaction equation
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[C:16]([C:19]1[CH:20]=[C:21]([CH:28]=[CH:29][CH:30]=1)[CH2:22][CH:23]([C:25]([OH:27])=[O:26])[NH2:24])([OH:18])=[O:17]>>[C:25]([CH:23]([NH:24][C:25]([CH:23]([NH:24][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)[CH2:22][C:21]1[CH:28]=[CH:29][CH:30]=[C:19]([C:16]([OH:18])=[O:17])[CH:20]=1)=[O:26])[CH2:22][C:21]1[CH:28]=[CH:29][CH:30]=[C:19]([C:16]([OH:18])=[O:17])[CH:20]=1)([OH:27])=[O:26]

Participants

3

Reactant 2

HCID 2652743-(3-Carboxyphenyl)alanineHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

Product 1

HCID 45255381HCID 45255381, compound

Procedure

In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 3-carboxy-DL-phenylalanine to provide the title compound in good yield.

Sources & evidence

ORD record
ord-e89bc33231a349e284bedb7c8ea0c5b7
Source dataset
uspto-grants-2012_10
Patent number
US08288549B2

Reaction notes

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