2-amino-3-(3-methoxyphenyl)propanoic acid → HCID 45255382, compound

HRID 2065641Notes

Reaction equation

HRID 2065641 reaction equation
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH:27]=[CH:28][CH:29]=1)[CH2:21][CH:22]([C:24]([OH:26])=[O:25])[NH2:23]>CS(C)=O>[C:24]([CH:22]([NH:23][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)[CH2:21][C:20]1[CH:27]=[CH:28][CH:29]=[C:18]([O:17][CH3:16])[CH:19]=1)([OH:26])=[O:25]

Participants

4

Reactant 2

HCID 5541842-amino-3-(3-methoxyphenyl)propanoic acidHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

Product 1

HCID 45255382HCID 45255382, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

In close analogy to the procedure described in Example 32, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 3-methoxy-DL-phenylalanine in DMSO to provide the title compound in good yield.

Sources & evidence

ORD record
ord-29393ad17a0c481296bf5d06b3d7e0f5
Source dataset
uspto-grants-2012_10
Patent number
US08288549B2

Reaction notes

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