HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Tyrosine, DL- → 2-[1-Carboxy-2-(3-hydroxy-phenyl)-ethylamino]-6-chloro-quinoline-3-carboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Tyrosine, DL- | HCID 13052 | — |
| Edukt | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Produkt | 2-[1-Carboxy-2-(3-hydroxy-phenyl)-ethylamino]-6-chloro-quinoline-3-carboxylic acid | HCID 45255582 | — |
Reaktionsschritte
In close analogy to the procedure described in Example 32, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 3-hydroxy-DL-phenylalanine and crude product is separated by flash chromatography on SiO2 to provide the title compound in low yield.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08288549B2 |
| Quelldatensatz | uspto-grants-2012_10 |
| ORD ID | ord-6d5e19db7e3c4509a4c651291bf9647b |
| Quellennotiz | uspto-grants-2012_10 |