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3-Tyrosine, DL- → 2-[1-Carboxy-2-(3-hydroxy-phenyl)-ethylamino]-6,8-dichloro-quinoline-3-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Tyrosine, DL- | HCID 13052 | — |
| 反応物 | 2,6,8-Trichloroquinoline-3-carboxylic acid | HCID 86656379 | — |
| 生成物 | 2-[1-Carboxy-2-(3-hydroxy-phenyl)-ethylamino]-6,8-dichloro-quinoline-3-carboxylic acid | HCID 45255583 | — |
反応手順
In close analogy to the procedure described in Example 1, 2,6,8-trichloroquinoline-3-carboxylic acid is reacted with 3-hydroxy-DL-phenylalanine to provide the title compound in moderate yield. LCMS m/z 421 (M+1).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08288549B2 |
| 出典データセット | uspto-grants-2012_10 |
| ORD ID | ord-25b4d7792a9b4a498c1f83716b1054c5 |
| 出典メモ | uspto-grants-2012_10 |