HCID 23009436, compound → HCID 45255584, compound

HRID 2065645Notes

Reaction equation

HRID 2065645 reaction equation
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[NH2:16][CH:17]([CH2:21][C:22]1[CH:23]=[CH:24][C:25]2[O:29][C:28]([CH3:30])=[N:27][C:26]=2[CH:31]=1)[C:18]([OH:20])=[O:19]>>[C:18]([CH:17]([NH:16][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)[CH2:21][C:22]1[CH:23]=[CH:24][C:25]2[O:29][C:28]([CH3:30])=[N:27][C:26]=2[CH:31]=1)([OH:20])=[O:19]

Participants

3

Reactant 2

HCID 23009436HCID 23009436, compoundHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

Product 1

HCID 45255584HCID 45255584, compound

Procedure

In close analogy to the procedure described in Example 32, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 2-amino-3-(2-methyl-benzooxazol-5-yl)-propionic acid to provide the title compound in good yield.

Sources & evidence

ORD record
ord-9aafd4657ce64e659b15eb799d790566
Source dataset
uspto-grants-2012_10
Patent number
US08288549B2

Reaction notes

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